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University of Southern California

Genevestigator  

Last Updated: Nov 23, 2011 URL: http://norris.usc.libguides.com/Genevestigator Print Guide RSS UpdatesShareThis

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GeneVestigator-Multi-organism microarray database and expression meta-analysis

Main Applications

  • Functional genomics: Use Meta-Profile Analysis to compare independent microarray experiments and explore expression patterns of user gene(s) under specific biological conditions
  • Biomarker discovery and validation: Identify genes specifically expressed in given test conditions vs. user specified control conditions
  • Find Reference genes for qPCR: Ad hoc search of the most stably-expressed genes according to user specified conditions
  • Gene modules and network analysis: Use Bi-clustering Analysis to identify co-expressed genes under various experimental conditions

Noteworthy Features

  • Comprehensive database: Covering 14 organisms (including many plant species) and > 60,000 microarray data sets
  • Normalized data: Allowing meta-analysis of independent datasets
  • Manually-curated ontology: Data are manually curated for anatomy, development, conditions, genotypes, and neoplasm status.  Stringent Q/C applied.

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