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Ingenuity Variant Analysis (IVA): Overview

Main Applications

Ingenuity Variant Analysis (IVA) is a web-based functional analysis tool for quickly identifying causal variants from human sequencing data.

Identify and prioritize variants from WGS, exome- and targeted-sequencing data

  • Direct upload of VCF files
  • Annotate and interactively filter variants
  • Link variants to biology using the human-curated Ingenuity Knowledge Base
  • Identify variants in genes that interact with those genes known to be associated with Causal Network Analytics (provided by IPA)

Why use IVA?

  • Up-to-date high quality knowledgebase manually curated by PhD scientists
  • Intuitive, use-friendly interface
  • Interactive filter cascade (wide selection of basic and advanced filters)
  • Analyze thousands of samples simultaneously

Access IVA @ USC

USC has licensed IVA for the free use of USC faculty, students and staff.  The license allows an unlimited number of concurrent users BUT the maximum number of active samples is 50 at any given moment for the ENTIRE USC.  

To Apply for your IVA Account:

  1. Carefully read the IVA user policy
  2. Complete and submit the IVA registration form
  3. Ingenuity System will send out an account activation link within 2 business days upon receiving your registration request
  4. Activate your account following the instruction.

To Use IVA:

  1. Submit your IVA Access Request
  2. You will be notified on the access instruction within two business days.

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