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Ingenuity Variant Analysis (IVA): Overview

Main Applications

Ingenuity Variant Analysis (IVA) is a web-based functional analysis tool for quickly identifying causal variants from human sequencing data.

Identify and prioritize variants from WGS, exome- and targeted-sequencing data

  • Direct upload of VCF files
  • Annotate and interactively filter variants
  • Link variants to biology using the human-curated Ingenuity Knowledge Base
  • Identify variants in genes that interact with those genes known to be associated with Causal Network Analytics (provided by IPA)

Why use IVA?

  • Up-to-date high quality knowledgebase manually curated by PhD scientists
  • Intuitive, use-friendly interface
  • Interactive filter cascade (wide selection of basic and advanced filters)
  • Analyze thousands of samples simultaneously

Access IVA @ USC

USC has licensed IVA for the free use of USC faculty, students and staff.  The license allows unlimited number of concurrent users with a maximum number of 50 samples at any given moment for the ENTIRE USC.  To access IVA:

  1. Fill out the IVA registration form
  2. Ingenuity System will send out an account activation link within 2 business days upon receiving your registration request
  3. Activate your account following the instruction
  4. Log in here to use IVA

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