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Golden Helix SNP and Variation Suite (SVS)  

Last Updated: Sep 28, 2012 URL: http://norris.usc.libguides.com/SVS Print Guide RSS UpdatesShareThis

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Golden Helix SNP and Variation Suite (SVS)

Main Applications

  • HelixTree: core application for genetic association studies
  • CNAM: processing raw intensity data, identifying and visualizing regions of copy number variation, performing association analysis.
  • Whole Genome Analysis Module: performing GWAS analysis
  • Sequence Analysis Module: advanced functional analysis tools for next-gen sequencing data (VCF files)
  • PBAT: statistical analysis for family-based SNP and CNV association studies
  • Regression Module: advanced linear and logistic regression
  • SVS Viewer: free visualization tool for data sharing

Noteworthy Features

  • Comprehensive suite of advanced analytic tools for managing, analyzing, and visualizing large-scale, complex genomic variation data. 
  • Broad collection of intuitive workflows for SNP, LD, CNV, GWAS, Family-based, Homozygosity and many more genome variation analyses. 
  • Efficient and easy-to-use data management and editing functions
  • Fast and memory efficient algorithms for handling high-dimensional genomic data on a personal computer.
  • Fully-programmatic scripting interface for advanced Python users
  • Supporting direct data import from all major array platforms
  • Supporting Windows, Mac OS and Linux.
 

Access SVS @ USC

USC has licensed PGS for the free use of USC faculty, students and staff. The license consists of ONE concurrent user seats.  There are three ways you can access PGS:

  1. On your own computer
    (requires local installation of SVS)
  2. On NML-Bioinfo workstations computers
    (no installation needed)
    Available in the Norris Medical Library's Bioinformatics Computation and Consulting Center (top floor)
  3. On HPCC-NML
    (no installation needed)
    Requires HPCC account AND access to the HPCC-NML Bioinformatics Computing Resource.  Account processing may take 1-3 weeks.

To get your account:

  1. Carefully check out the SVS user policy
  2. Fill out the SVS registration form
 

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