What's new in Vector NTI 11.5

•  Runs directly on Mac OS X with Parallels® 5 for Mac installation.  No more reboot for Mac users.
  
• Improved workflow for querying existing TaqMan Gene Expression Arrays and managing custom designs. 
• Support Applied Biosystems 3500 .ab1 files.
  
• Improved display for primer-template alignment at single-base resolution in Molecular Viewer

Main Applications

• Vector NTI: Sequence creation, mapping, analysis, design, annotation, illustration.
• AlignX: Multiple sequence alignment of proteins and DNAs.
• ContigExpress: DNA sequence assembly, SNP and mutation detection, and sequencing project management.
• GenomBench:  Analysis and annotation of reference genomic DNA sequences.
• BioAnnotator: Functional annotation of DNA and protein sequences.
• Vector NTI Explorer: Molecular biology data retrieval and management.

Key Features

• Store and manage sequence and other data: DNA/RNAs; proteins; restriction enzymes; oligos; gel markers; citations; BLAST and other analysis results.
• Analyze, create, map, edit, annotate, illustrate, share and publicize DNA and protein sequences.
• Perform BLAST searches of public or private databases, including proprietary clone collections, and save the results to the Vector NTI Local Database.
• Design primers in batch for PCR, cloning, sequencing or hybridization experiments.
• Design recombinant cloning strategies in silico using a built-in database of biological knowledge. You can even run your gels on the computer.
• View and analyze your own proprietary data in the context of reference genomic sequence information.
• Align multiple protein or DNA sequences and then view individual annotated features within the alignment.
• Search NCBI's entrez system directly from your desktop, then view and save DNAs, proteins and citations.
• Assemble and edit chromatogram data into contigs for the analysis of de novo sequence data.
• Perform functional annotation of protein and DNA sequences using a large number of analysis tools and protein motif database.

• Sequence Management: Analyze, create, map, edit, annotate, illustrate, share and publicize DNA and protein sequences.
   
• Primers Design: single or batch design of amplification, sequencing, MultiPlex PC, RHybridization, Alignment PCR primers. 
• In silico Cloning: quick selection of vectors with specificied features (e.g. RE sites, drug resistance markers, promoters, tags, etc.), predict cloning results with Gel Simulation
• Multiple Sequence Alignment: by ClusterW algorithm with detailed statistics and visualization report
• Sequence Search: comprehensive search of private databases for proprietary clone collections, and of public databases such as NCBI's Entrez system for sequence similarity and PubMed for citations.
• Contig Assembly: easy assembly and edit chromatogram data into contigs by CAP3 algorithm.
• Protein Analysis: visualize 3-D protein structure and analyze protein functions.